Table 1.

Summary of clinical characteristics and radiologic features of previously reported cases of serous cystic neoplasm mimicking intraductal papillary mucinous neoplasm.

Reference	Age/Sex	Clinical manifestations	Laboratory findings	CT findings	MR findings	ERCP findings	EUS findings	FNA findings	Treatment	Pathologic findings	Follow-up
Furukawa et al[3]	76/M	Vague abdominal pain	NA	Multicystic enhanced mass composed of a spongy meshwork with central scar	NA	Communication between pancreatic duct and the cystic cavity	NA	NA	Pancreatico-duodenectomy	Serous cystadenoma communicated with the pancreatic duct	NA
Hashimoto et al[24]	42/F	Incidental finding	No elevation of levels of amylase, lipase, or tumor markers	Multiple cystic tumors, the wall of which had no enhancing solid component	Cystic tumor of low intensity on T1-weighted images and high intensity on T2-weighted images	The deviation of the MPD and inflow of the contrast material into the cystic part of the tumor	NA	NA	Pylorus-preserving pan creaticoduodenectomy	Serous cystadenoma communicated with the pancreatic duct	Doing well 12 mo after surgery
JaeHong Jung et al[5]	44/F	Right upper quadrant pain and radiating pain	Elevation of serum amylase and lipase levels No elevation of CA 19-9 level	Multilocular cystic mass in the body of the pancreas with dilated pancreatic duct	NA	The inflow of the contrast material into the cystic part of the tumor	NA	NA	Distal pancreatectomy	Serous cystadenoma communicated with the pancreatic duct	NA
Stephanie Truant et al[4]	66/F	Transient epigastric pain	No elevation of CEA and CA 19-9 levels	Well-defined, multiloculated, cystic mass	Upstream dilatation of the main pancreatic duct	Cystic dilatation of pancreatic branches communicating with the dilated MPD	Microcystic pattern concluded in serous cystadenoma	CEA (0.2 ng/mL)	Distal pancreatectomy	Serous cystadenoma with external compression of the MPD	Doing well 6 mo after surgery
Berman et al[2]	65/F	Right upper quadrant pain	NA	Cystic mass in the head and neck of the pancreas	Side-branch communication between the cystic lesion and the pancreatic duct	NA	NA	NA	Pancreatico-duodenectomy	Serous cystadenoma in direct communication with the pancreatic duct	Doing well 8 mo after surgery
Matsubayashi et al[22]	59/F	Incidental finding	Mild elevation of CEA level (7.5 ng/mL)	Multilocular cyst with partially thickened septum	Cystic lesion with dilated upstream MPD	Compressed, atrophic Wirsung duct and stenotic Santorini duct, connection with the multilocular cyst at the pancreatic head	Macroscopic multilocular cyst with honeycomb- like components and irregularly dilated MPD with lobularity and high echoic foci	High level of amylase (347000 U/L), CA 19-9 (30796 U/mL), but low level of CEA (4.5 ng/mL)	Pancreatico-duodenectomy	Serous cystadenoma communicated with the pancreatic duct	Doing well 3 yr after surgery
Case 1	54/M	Incidental finding	No elevation of CEA and CA 19-9 levels	Multiloculated, cystic mass in the body of the pancreas	Communication between the cystic lesion and the pancreatic duct	NA	Microcystic pattern with central scar in pancreatic lesion	NA	Distal pancreatectomy	Serous cystadenoma without connection with the MPD	Doing well 6 mo after surgery
Case 2	42/F	Incidental finding	No elevation of CEA and CA 19-9 levels	Multiloculated, cystic mass in the body of the pancreas	Communication between the cystic lesion and the pancreatic duct	NA	NA	NA	Median pancreatectomy	Serous cystadenoma without connection with the MPD	Doing well 6 mo after surgery

CA 19-9, carbohydrate antigen 19-9, CEA = carcinoembryonic antigen, CT = computed tomography, ERCP = endoscopic retrograde cholangiopancreatography, EUS = endoscopic ultrasonography, FNA = fine-needle aspiration, IPMN = intraductal papillary mucinous neoplasm, MPD = main pancreatic duct, MR = magnetic resonance, NA = not available, SCN = serous cystic neoplasm.