Table 2.

Indications for endoscopic ultrasonography-fine-needle aspiration of pancreatic cysts by different guidelines.

Guidelines	AGA (2015)[20]	IAP (2017)[8]	European (2018)[9]
	At least 2 of the following features:	• Growth rate ≥ 5 mm/2 yr	• If the results are expected to change clinical management
	• Cyst diameter > 30 mm	• Serum CA 19-9 level↑
		• PD dilatation 5–9 mm
	• PD dilatation	• Cyst diameter ≥ 30 mm
			• If there are clinical or radiological features of concern during the initial investigation or surveillance
		• Enhancing mural nodule < 5 mm
	• Solid nodule
		• Lymphadenopathy
		• Abrupt change of PD diameter and distal pancreatic atrophy
		• Thickened or enhancing wall of cyst

AGA = American Gastroenterological Association Institute guideline on the diagnosis and management of asymptomatic neoplastic pancreatic cysts, CA 19-9, carbohydrate antigen 19-9, European = European evidence-based guidelines on pancreatic cystic neoplasms, EUS = endoscopic ultrasonography, FNA = fine-needle aspiration, IAP = Revisions of International Consensus Fukuoka Guidelines for the Management of intraductal papillary mucinous neoplasm of the pancreas, PD = pancreatic duct.