Table 2.
Comparison data of questionnaire and inflammatory marker at baseline and after 8 weeks.
| Characteristics | Baseline | After 8 weeks | Difference (95% CI) | P value |
|---|---|---|---|---|
| LCQ | ||||
| Physical | 5.44 (4.88–6.00) | 5.50 (4.78–5.91) | 0.10 (−0.20, 0.41)a | .492* |
| Psychological | 5.57 (4.96–6.61) | 5.79 (4.93–6.43) | 0.01 (−0.35, 0.37)a | .957* |
| Social | 6.00 (5.50–6.75) | 6.00 (5.31–7.00) | 0.00 (0.00, 0.25)b | .720** |
| Total | 16.77 (15.63–19.13) | 17.55 (15.24–18.94) | 0.12 (−0.73, 0.97)a | .772* |
| SGRQ | ||||
| Symptoms | 46.44 (35.08–55.96) | 46.76 (28.70–57.14) | −1.78 (−8.62, 5.06)a | .599* |
| Activity | 45.10 (28.52–61.34) | 50.62 (28.68–63.19) | −0.86 (−5.25, 5.72)b | .876** |
| Impact | 13.55 (6.08–23.78) | 15.95 (6.05–33.08) | 1.81 (−2.26, 8.33)b | .058** |
| Total | 30.59 (19.41–37.82) | 29.88 (19.57–41.78) | 1.90 (−1.02, 4.83)a | .194* |
| WBC | 7.40 (6.26–8.17) | 7.08 (5.93–8.96) | 0.29 (−0.41, 0.99)b | .364** |
| IL-6 | 5.60 (4.20–9.50) | 5.30 (3.53–7.40) | −0.35 (−1.50, 1.30)b | .946** |
| CRP | 0.24 (0.14–0.53) | 0.15 (0.07–0.43) | −0.02 (−0.18, 0.02)b | .416** |
Data are presented as median (interquartile range); Shapiro–Wilk’s test was employed for test of normality assumption.
CI = confidence interval, CRP = C-reactive protein, IL-6 = interleukin-6, LCQ = Leicester cough questionnaire;, SGRQ = St. George respiratory questionnaire, WBC = white blood cell.
a
Differences with 95% confidence interval were derived from paired t test.
b
Differences with 95% confidence interval were derived by Wilcoxon’s signed rank test.
*
P values were derived from paired t test.
**
P values were derived by Wilcoxon’s signed rank test.