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. 2023 Jan 30;2023:9645789. doi: 10.1155/2023/9645789

Figure 2.

Figure 2

Activation of AMPK pathway by RRP promotes autophagy delaying vascular senescence. (a) Detection of AMPKα and m-TOR levels in total vascular proteins of mice by western blot. Data are shown as mean values ± SD per group and expressed as fold-over the control mean. (b) The amounts of AMPKα and m-TOR in the mRNA of mouse vasculature were detected by qRT-PCR in each group. Data are shown as mean values ± SD per group and expressed as fold-over the model mean. (c) Levels of autophagy-related proteins p62, beclin-1, and LC3B in total vascular proteins of mice. Data are shown as mean values ± SD of three animals per group and expressed as fold-over the control mean (∗p < 0.05 and ∗∗p < 0.001 vs. control; #p < 0.05 and ##p < 0.001 vs. model by one-way ANOVA test).