Table 1.
Demographic, diagnostic and treatment characteristics of sample.
| Controls | Cases | Difference | |
|---|---|---|---|
| N | 1761 | 1260 | |
| Age, mean (SD) | 32.99 (12.05) | 32.12 (11.74) | Z = 3.73, p < 0.001a |
| BMI, mean (SD) | 24.99 (4.97) | 25.16 (5.62) | Z = 3.39, p < 0.001a |
| Normal weight, N (%) | 1030 (58.49%) | 716 (56.82%) | χ2 = 8.88, p = 0.012 |
| Overweight, N (%) | 486 (27.60%) | 322 (25.56%) | |
| Obese, N (%) | 245 (13.91%) | 222 (17.62%) | |
| Sex, N (%) female | 885 (50.26%) | 437 (34.68%) | χ2 = 71.75, p < 0.001 |
| Treatment at time of scanning, N (%) | |||
| Unmedicated | – | 98 (8.49%) | – |
| Atypical antipsychotics | – | 722 (62.51%) | – |
| Typical antipsychotics | – | 259 (22.42%) | – |
| Atypical and typical antipsychotics | – | 76 (6.58%) | – |
| Antipsychotic dose, chlorpromazine eq. (mg) mean (SD) | – | 454.23 (952.51) | – |
| Illness duration years, mean (SD) | – | 7.01 (11.24) | – |
| PANSS (Positive), mean (SD) | – | 14.39 (32.98) | – |
| PANSS (Negative), mean (SD) | – | 16 (33.15) | – |
| PANSS (Total), mean (SD) | – | 57.58 (37.76) | – |
| SAPS, mean (SD) | – | 20.91 (15.61) | – |
| SANS, mean (SD) | – | 15.26 (13.1) | – |
aModel coefficients obtained from model controlling for a random effect of site. PANSS Positive and Negative Syndrome Scale, SAPS Scale for the Assessment of Positive Symptoms, SANS Scale for the Assessment of Negative Symptoms