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. 2022 Nov 19;128(2):342–353. doi: 10.1038/s41416-022-02031-x

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Low FOLR1 gene expression in normal tissues (grey) compared to primary ovarian tumours (red) (N numbers indicated in parentheses; The Human Protein Atlas online tool Xenabrowser online tool [35] (Xenabrowser.net). b No membrane or cytoplasmic FRα protein expression on a broad range of normal tissues (N = 142; scale bars = 2.5 mm). Key normal tissue types; fallopian tube (Fa), ovary (Ov), liver (Li), lung (Lu) and kidney (Ki) are highlighted with black boxes and zoomed images shown. c Representative images of ovarian tumour FRα staining (×40 magnification; scale bar = 50 μm). Bl bladder, Bo bone marrow, B brain, Br breast, Cb cerebrum; Ce cervix; Co colon; En endometrium, Fa fallopian tube, Il ileum, Ki kidney, Li liver, Lu lung, Ly lymph node, Mu muscle, striated, Oe oesophagus, Ov ovary, Pa pancreas, Pl placenta, Pr prostate, Re rectum, Sk skin, Sm small intestine, SC spinal cord, Sp spleen, St stomach, Te testis, Th thymus, Thy thyroid, Ur ureter.