Figure 4.

Novel contribution of sht in GBS to evasion of phagocytosis. Mutation in sht enhances the recovery of GBS from monocytes in comparison to WT (n = 4). U937 human monocytes were infected with a multiplicity of infection (MOI) of ~ 100 and extracellular bacteria were killed by antibiotic treatment, followed by quantification of iGBS at 6 h, 12 h, 24 h and 48 h post-infection. Bars show mean and SEM and unpaired t tests compared WT to Δsht at each timepoint (*P ≤ 0.05).