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. 2023 Feb 6;14(2):86. doi: 10.1038/s41419-023-05631-4

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A, B Human peripheral HLA-DR^-CD11b⁺CD33⁺ MDSCs and CD4⁺IL-17A⁺ Th17 cells (HC n = 40, SS n = 40) were detected by flow cytometry. Representative flow cytometric analysis and percentages of MDSCs in HC and SS patients were shown. C–E The relationships of MDSCs with Th17 cells, EULAR Sjögren’s Syndrome Disease Activity Index (ESSDAI) and serum IgG were analyzed (n = 40). F–H SS patients were divided into antibodies-positive (+) and antibodies-negative (–) two groups, whose percentages of MDSCs were compared. **p < 0.01, ****p < 0.0001.