Table 4.
Comparison of resting cardiac function, biomarker profile, and biventricular diastolic and systolic reserve between Allo-SCT survivors and Controls.
| Allo-SCT survivors | Controls | P | |
|---|---|---|---|
| Cardiac biomarkers | |||
| cTn-I, ng L−1 | 2 (1 − 4) | 2 (2 − 4) | 0.52a |
| BNP, ng L−1 | 22 (15 − 37) | 19 (14 − 36) | 0.80a |
| Resting echocardiography | |||
| LVEF, % | 56 ± 6 | 59 ± 5 | 0.16 |
| GLS, % | − 19 (− 18 − − 20) | − 20 (− 18 − − 21) | 0.13a |
| HR, beats min−1 | 68 ± 8 | 63 ± 10 | 0.16 |
| ExCMR | |||
| LVEDVI reserve, mL m−2 | − 1 ± 4 | 3 ± 3 | 0.006 |
| RVEDVI reserve, mL m−2 | − 4 ± 8 | − 2 ± 7 | 0.46 |
| LVESVI reserve, mL m−2 | − 6 ± 3 | − 5 ± 3 | 0.47 |
| RVESVI reserve, mL m−2 | − 8 ± 5 | − 10 ± 5 | 0.35 |
Data are mean ± SD or median (IQR); Abbreviations: BNP B-natriuretic peptide, cTn-I cardiac troponin-I, GLS global longitudinal strain, ExCMR exercise cardiac magnetic resonance imaging, HR heart rate, LVEDVI left-ventricular end-diastolic volume index, LVEF left-ventricular ejection fraction, LVESVI left-ventricular end-systolic volume index, RVEDVI right-ventricular end-diastolic volume index, RVESVI right-ventricular end-systolic volume index.
aanalysed using Mann–Whitney U test.