Table 5.
Changes in anthropometric and clinical variables before and after bariatric surgery.
| Variable | Preoperation (n=59) | Postoperation (n=37) | P value* | ||||
|---|---|---|---|---|---|---|---|
| Mean | SD | Range | Mean | SD | Range | ||
| Anthropometric measurements | |||||||
| BMI (kg/m2) | 41.31 | 7.57 | 28.09-59.99 | 27.78 | 4.24 | 19.79-36.11 | <0.001 |
| Weight (kg) | 122.12 | 24.04 | 80.00-183.20 | 84.33 | 15.48 | 58.00-120.00 | <0.001 |
| %EWL | 85.0 | 37.6 | 8.6-199.7 | ||||
| %TWL | 30.3 | 14.1 | 1.6-59.6 | ||||
| %EBMIL | 88.0 | 36.3 | 23.7-198.7 | ||||
| Waist circumference (cm) | 123.7 | 18.2 | 83.5-170.0 | 101.9 | 15.3 | 75.5-130.0 | <0.001 |
| Hip circumference (cm) | 127.5 | 15.4 | 93.5-162.0 | 106.6 | 11.9 | 92.5-135.5 | <0.001 |
| Sex hormones | |||||||
| Testosterone (ng/ml) | 2.87 | 1.00 | 1.22-5.93 | 5.45 | 0.84 | 3.97-7.2 | <0.001 |
| Estradiol (pg/ml) | 42.62 | 27.22 | 10.50-155.48 | 32.58 | 11.90 | 12.00-55.35 | 0.036 |
| Prolactin (ng/ml) | 11.59 | 5.95 | 4.51-40.95 | 8.33 | 4.45 | 0.20-21.41 | <0.001 |
| Progesterone (ng/ml) | 0.49 | 0.51 | 0.05-3.58 | 4.45 | 8.34 | 0.20-4.28 | 0.310 |
| LH (mIU/ml) | 4.54 | 2.08 | 1.64-12.11 | 5.66 | 1.36 | 2.89-8.67 | 0.005 |
| FSH (mIU/ml) | 5.21 | 2.82 | 1.29-13.58 | 6.73 | 2.97 | 2.25-16.73 | <0.001 |
| Blood glucose metabolism, hemoglobin, and CRP | |||||||
| HbA1c (%) | 6.78 | 1.76 | 4.80-11.60 | 4.23 | 0.17 | 4.3-6.3 | <0.001 |
| Basal insulin (mIU/L) | 22.33 | 13.09 | 4.58-73.71 | 7.03 | 5.56 | 1.37-29.32 | <0.001 |
| FPG (mmol/L) | 7.17 | 2.77 | 4.10-14.84 | 5.13 | 0.79 | 4.04-27.20 | <0.001 |
| HOMA-IR | 5.52 | 10.29 | 5.25-50.59 | 0.82 | 1.05 | 0.10-4.70 | 0.010 |
| Hemoglobin (g/L) | 154.99 | 11.75 | 127.70-179.00 | 150.40 | 12.00 | 122.00-173.00 | 0.082 |
| CRP (mg/L) | 8.85 | 11.49 | 0.70-71.82 | 2.52 | 4.38 | 0.24-21.23 | 0.008 |
| Vitamins and microelements | |||||||
| Vitamin A (nmol/L) | 1.33 | 0.53 | 0.40-2.25 | 1.36 | 0.47 | 0.42-2.31 | 0.204 |
| Vitamin B1 (nmol/L) | 70.43 | 19.02 | 45.25-129.09 | 70.08 | 17.01 | 45.98-111.62 | 0.478 |
| Vitamin B2 (ng/L) | 331.50 | 58.58 | 196.96-498.32 | 292.73 | 56.96 | 197.00-422.67 | 0.004 |
| Vitamin B6 (nmol/L) | 31.02 | 15.70 | 11.25-61.91 | 30.25 | 11.14 | 12.42-53.92 | 0.793 |
| Vitamin C (nmol/L) | 51.58 | 13.95 | 31.07-85.58 | 56.65 | 17.15 | 30.51-96.62 | 0.187 |
| Vitamin E (ng/ml) | 13.12 | 1.88 | 9.54-16.84 | 12.85 | 1.85 | 9.33-16.16 | 0.727 |
| 1, 25-(OH2) D3 (ng/ml) | 16.14 | 6.46 | 4.69-35.90 | 35.20 | 65.41 | 6.74-360.05 | 0.116 |
| Vitamin B12 (pg/ml) | 414.08 | 213.65 | 211.48-1244.86 | 282.78 | 187.87 | 2.72-736.08 | 0.002 |
| Ferritin (ng/ml) | 283.72 | 178.40 | 13.75-1082.88 | 171.23 | 101.67 | 26.42-389.04 | <0.001 |
| Fe (μmol/L) | 17.71 | 6.23 | 7.70-36.20 | 20.68 | 6.58 | 11.50-37.10 | 0.051 |
| Zn (μmol/L) | 9.57 | 3.33 | 4.90-23.00 | 9.23 | 3.87 | 4.47-27.20 | 0.790 |
| Cu (μmol/L) | 15.96 | 3.70 | 10.10-26.60 | 15.10 | 4.42 | 2.10-25.50 | 0.172 |
| Lipid metabolism | |||||||
| Total cholesterol (mmol/L) | 5.07 | 1.24 | 1.12-8.95 | 4.65 | 0.80 | 2.03-7.37 | 0.168 |
| Triglyceride (mmol/L) | 2.58 | 1.88 | 0.58-8.84 | 1.45 | 0.96 | 0.50-4.61 | 0.001 |
| HDL-c (mmol/L) | 1.09 | 0.50 | 0.64-3.09 | 1.16 | 0.62 | 0.59-1.73 | 0.788 |
| LDL-c (mmol/L) | 3.02 | 0.79 | 0.96-5.22 | 2.63 | 0.59 | 1.49-4.46 | 0.053 |
HOMA-IR, homeostasis model assessment of insulin resistance; 1, 25-(OH2) D3, 1, 25 - dihydroxy - vitamin D; Fe, iron; Zn, zinc; Cu, Copper
*:paired t-test.
%EWL, percentage of excess weight loss; %TWL, percentage of total weight loss; %EBMIL, percentage of excess BMI loss; FPG, fasting plasma glucose; LH, luteinizing hormone; FSH, follicle-stimulating hormone; CRP, C-reactive protein; HDL-c, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol.