Table 2.

Correlation between admission HO-1, HPX, and heme levels and markers of hemostatic activation in COVID-19.

Parameter	HO-1		HPX		Heme
	Rs *	P	Rs *	P	Rs *	P
Platelet count	−0.437	0.001	−0.001	0.996	−0.170	0.218
Prothrombin time	0. 345	0.010	0.050	0.716	−0.211	0.123
aPTT	0. 372	0.005	0.101	0.458	−0.233	0.086
Fibrinogen	0. 717	<0.001	0.283	0.034	−0.023	0.916
Factor VIII activity	0. 526	<0.001	0.172	0.204	0.220	0.106
Von Willebrand factor, antigen	0. 765	<0.001	0.166	0.214	0.081	0.550
Von Willebrand factor, activity	0. 762	<0.001	0.229	0.089	0.171	0.212
uPAR (urokinase receptor)	0. 606	<0.001	0.033	0.806	−0.107	0.429
D-dimer	0.263	0.184	−0.246	0.206	0.024	0.906
C-reactive protein	0.291	0.148	−0.143	0.474	0.133	0.516

HO: Heme-oxygenase; HPX: hemopexin; aPTT: activated partial thromboplastin time.

Significant correlations are highlighted in bold.

^*R_s: Spearman correlation coefficient.