Table A1.
The Included Parameters in the Data Sets with Their Descriptions, Additional Information, and Variable Type.
| Parameter | Description | Comment | Variable Type |
|---|---|---|---|
| Sex (female) | Percentage of female patients | N/A | Categorical |
| BMI | Body Mass Index | N/A | Numerical |
| Age (Q1, Q3) | Median age with 25th and 75th percentiles | N/A | Numerical |
| SOFA | Total SOFA score | Ignores missing components | Numerical |
| APACHE | Total APACHE II score | Ignores missing components | Numerical |
| GCS score | Total Glasgow Coma Scale-score | N/A | Numerical |
| ABP mean (mm Hg) | Arterial blood pressure (mean) | N/A | Numerical |
| Heart rate (/min) | Heart rate | Either ECG, unspecified, or monitor | Numerical |
| Hemoglobin (mmol/l) | Hemoglobin | Either arterial, blood, mixed venous, unspecified, venous, or bloodgas | Numerical |
| AKI | The creatinine component of the AKI (Acute Kidney Injury) score | N/A | Numerical |
| Urea/creatinine ratio | Urea over creatinine | N/A | Numerical |
| PO2 arterial (mm Hg) | Partial pressure O2 (arterial) | N/A | Numerical |
| Mean airway pressure (cmH2O) | Mean airway pressure | N/A | Numerical |
| Peak pressure (cmH2O) | Peak pressure | N/A | Numerical |
| PaO2/FiO2 | PaO2/FiO2 ratio | N/A | Numerical |
| Tidal volume (ml/kg) | Tidal volume per ideal body weight | N/A | Numerical |
| PCO2 arterial (mm Hg) | Partial pressure CO2 (arterial) | N/A | Numerical |
| End tidal CO2 (mm Hg) | End-tidal CO2 | N/A | Numerical |
| pH arterial | pH arterial | N/A | Numerical |
| Respiratory system compliance (ml/cmH2O) | Respiratory system compliance | Either dynamic or unspecified | Numerical |
| Driving pressure (cmH2O) | Driving pressure | N/A | Numerical |
| Respiratory rate (/min) | Respiratory rate | Measured by ventilator | Numerical |
| Ventilatory ratio | Ventilatory ratio | Calculated as: (minute ventilation (ml/min) · PaCO2 (mm Hg))/(predicted body weight · 100 · 37.5) | Numerical |
| Mechanical power (joules/minute/kg PBW) | Mechanical power per predicted body weight | N/A | Numerical |
| CRP (mg/l) | C-reactive protein | Either blood or unspecified | Numerical |
| Temperature (°C) | Temperature in degrees Celsius | Either unspecified, rectal, esophageal, nasopharyngeal, groin, bladder, core, blood, axillary, or ear | Numerical |
| Lymphocytes (%) | Lymphocytes percentage | N/A | Numerical |
| APTT | Activated partial thromboplastin time | Either blood or unspecified | Numerical |
| Prothrombin time (sec) | Prothrombin time | N/A | Numerical |
| Anticoagulants | Percentage of patients with anticoagulants intake | Includes medications: heparin, dalteparin, enoxaparin, nadroparin, danaparoid, tinzaparin, clopidogrel, dipyridamole, carbasalate, epoprostenol, ticagrelor | Categorical |
| Fluids | Percentage of patients with fluids intake | Includes medications: erythrocytes, thrombocytes, blood, solutions, carbohydrates, electrolytes | Categorical |
| Vasopressors | Percentage of patients with vasopressors intake | Includes medications: isoprenaline, norepinephrine, dopamine, phenylephrine, dobutamine, epinephrine, ephedrine, milrinone, enoximone, vasopressin, desmopressin | Categorical |
| Diuretics | Percentage of patients with diuretics intake | Includes medications: furosemide, bumetanide | Categorical |
| Corticosteroids | Percentage of patients with corticosteroids intake | Includes medications: corticosteroids hydrocortisone, prednisolone, betamethasone, dexamethasone, betamethasone, dexamethasone, methylprednisolone, prednisolone, prednisone, hydrocortisone, cortisone, methylprednisolone | Categorical |
| Other immunosuppressives | Percentage of patients with other immunosuppressives intake | Includes medications: anakinra, tocilizumab | Categorical |
| Antibiotics | Percentage of patients with antibiotics intake | Includes medications: flucloxacillin, cefuroxime, cefotaxime, ceftazidime, ceftriaxone, meropenem, gentamicin, ciprofloxacin, vancomycin, metronidazole | Categorical |
| Antimycotics | Percentage of patients with antimycotics intake | Includes medications: amphotericin, miconazole, ketoconazole, fluconazole, voriconazole, anidulafungin | Categorical |
| Antivirals | Percentage of patients with antivirals intake | Includes medicationcyclovirvir, ganciclovir, valaciclovir, valganciclovir, ritonavir, oseltamivir, lopinavir, remdesivir | Categorical |
| Musclerelaxants | Percentage of patients with musclerelexants intake | Includes medications: suxamethonium, rocuronium | Categorical |
| Opioids | Percentage of patients with opioids intake | Includes medications: fentanyl, alfentanil, sufentanil, remifentanil, morphine, fentanyl, piritramide | Categorical |
| Sedatives | Percentage of patients with sedatives intake | Includes medications: ketamine, etomidate, propofol, esketamine, diazepam, lorazepam, midazolam, dexmedetomidine | Categorical |