TABLE 4.
Differences Between Profile Specifications and ADNI 2 Protocol Specifications
| Actor | Profile section for reference | ADNI 2 (58) |
|---|---|---|
| Site administrator | 3.6.1.1: site accreditation/qualification maintenance | Same |
| Site administrator | 3.6.2: imaging facility personnel | Same |
| Medical physicist | 3.6.3: amyloid PET acquisition scanner | Same |
| Medical physicist | 3.6.3.1.1: radionuclide calibrator | Same |
| Medical physicist | 3.6.3.1.2: scales and stadiometers | Not required |
| Medical physicist | 3.6.3.1.4: clocks and timing devices | Not required |
| Medical physicist | 3.6.4.1: uniformity and calibration | Not required |
| Medical physicist | 3.6.4.2: resolution | Same |
| Medical physicist | 3.6.4.3: noise | Same |
| Medical physicist | 3.6.4.4: amyloid PET specific phantom measurements | Same |
| Medical physicist | 4.1: performance assessment: image acquisition site | Same |
| Technologist | 3.1.3.1.2: radiopharmaceutical activity calculation or schedule | Dose structured report not required |
| Technologist | 3.1.3.1.3: radiopharmaceutical administration route | Excludes saline flush and checking for infiltration |
| Technologist | 3.2.1.1: timing of image data acquisition | Same |
| Technologist | 3.2.1.2: subject positioning | Does not cover strict serial scan positioning |
| Technologist | 3.2.1.3: scanning coverage and direction | Same |
| Technologist | 3.2.1.4: scanner acquisition mode parameters: PET acquisition | Same except does not cover if scan is stopped and restarted |
| Technologist | 3.2.1.4: scanner acquisition mode parameters: CT acquisition | Not required |
| Technologist | 3.3.1: imaging data reconstruction | Same except point spread function is allowed |
| Image Analyst | 4.4: performance assessment: image analysis workstation | Not required |