TABLE 5.

QIBA Profile Development Stages

Profile stages	Description
Public comment	Biomarker committee experts have drafted profile and believe it is practical and expect it to achieve claimed performance
Consensus	Wider community has read profile and judged it to be practical and expect it to achieve claimed performance
Technically confirmed	Several sites have performed profile and found it to be practical and expect it to achieve claimed performance (status of the profile)
Claim confirmed	Some sites have performed profile and found that it achieved claimed performance
Clinically confirmed	Many sites have performed profile and demonstrated claimed performance is widely achievable