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. 2023 Feb;64(2):252–259. doi: 10.2967/jnumed.122.264383

TABLE 2.

Patients with 68Ga-NODAGA-E[c(RGDyK)]2 PET–Positive Lesions (TLR ≥ 2) According to WHO Classification of NENs

Uptake ratio NET G1 (n = 21) NET G2 (n = 55) NET G3/NEC (n = 21) All (n = 97)
TLR ≥ 2 13 (62%) 42 (76%) 19 (91%) 74 (76%)
TLR < 2 8 (38%) 13 (24%) 2 (10%) 23 (24%)

A tumor was defined as positive when the TLR, measured as lesion SUVmax–to–normal liver SUVmean, was ≥ 2. Of the patients with NET G3/NEC tumors, 13 of 14 (93%) patients with NET G3 were positive and 6 of 7 (86%) patients with NEC were positive.