eTable 4. Total burden of disease (disability-adjusted life years [DALY] absolute numbers and relative contributions) for the selected causes of burden of disease (levels 3 and 4, Germany, both sexes).
| Cause of burden of disease (levels 3 and 4) | DALY | Proportion of level 3 to 4 (in percent) | ||||
| DALY | UI_lb | UI_ub | Proportion | UI_lb | UI_ub | |
| Lower respiratory infections | 224 306 | 222 505 | 238 565 | – | – | – |
| Tracheal, bronchial and lung cancer | 989 188 | 981 443 | 1 012 245 | – | – | – |
| Breast cancer | 473 366 | 454 905 | 527 690 | – | – | – |
| Prostate cancer | 265 264 | 246 455 | 300 985 | – | – | – |
| Colorectal cancer | 523 155 | 512 617 | 550 669 | – | – | – |
| Ischemic heart disease | 1 918 193 | 1 897 796 | 2 033 859 | – | – | – |
| Stroke | 735 883 | 727 508 | 799 155 | – | – | – |
| – subarachnoid hemorrhage | 79 902 | 78 564 | 93 831 | 10.9 | 10.3 | 12.3 |
| – intracerebral hemorrhage | 217 344 | 211 666 | 234 109 | 29.5 | 27.6 | 30.8 |
| – ischemic stroke | 438 638 | 425 609 | 484 579 | 59.6 | 57.6 | 61.6 |
| Hypertensive heart disease | 286 381 | 266 860 | 331 850 | – | – | – |
| Chronic obstructive lung disease | 829 714 | 696 238 | 965 784 | – | – | – |
| Alzheimer’s disease and other dementias | 623 515 | 539 034 | 711 638 | – | – | – |
| Alcohol use disorders | 427 545 | 366 548 | 501 661 | – | – | – |
| Depressive disorders | 469 767 | 391 219 | 607 266 | – | – | – |
| – dysthymia | 32 399 | 18 940 | 61 783 | 6.9 | 3.7 | 12.8 |
| – major depression | 437 369 | 350 627 | 562 627 | 93.1 | 87.2 | 96.3 |
| Anxiety disorders | 500 130 | 366 541 | 702 047 | – | – | – |
| Diabetes mellitus | 794 940 | 665 042 | 1 050 903 | – | – | – |
| – Type 2 diabetes mellitus | 753 404 | 633 899 | 991 637 | 94.8 | 92.8 | 95.9 |
| – Type 1 diabetes mellitus | 41 536 | 37 759 | 53 284 | 5.2 | 4.1 | 7.2 |
| Low back pain | 1 434 132 | 1 117 225 | 1 815 326 | – | – | – |
| Neck pain | 473 413 | 383 336 | 681 440 | – | – | – |
| Road injuries | 212 245 | 208 370 | 263 745 | |||
| – pedestrian road injury | 40 967 | 23 628 | 70 115 | 19.3 | 10.7 | 28.0 |
| – cyclist road injury | 28 518 | 25 406 | 40 668 | 13.4 | 11.1 | 17.7 |
| – motorcyclist road injury | 40 981 | 40 376 | 45 855 | 19.3 | 16.4 | 21.2 |
| – occupant road injury | 99 393 | 95 063 | 113 043 | 46.8 | 39.8 | 50.7 |
| – other road injury | 2387 | 1999 | 7353 | 1.1 | 0.9 | 3.2 |
| Other transport injuries | 16 461 | 15 485 | 26 584 | – | – | – |
| Headache disorders | 853 028 | 666 889 | 1 104 548 | – | – | – |
| – tension headache | 799 418 | 601 368 | 1 024 549 | 93.7 | 87.7 | 94.8 |
| – migraine | 53 610 | 44 542 | 98 706 | 6.3 | 5.2 | 12.3 |
ub, upper bound; lb, lower bound; UI, 95% uncertainty interval