Table 1.

Summary of Logistic Regression fits for All patients.

Independent Variables	# Variables	F Value	p-value	R2	AUC [95% LL, 95% UL]
3PC+Vol	2	16.08	0.0003	0.664	0.912 [0.792, 1.00]
Ecc+3PC	2	14.43	0.0007	0.614	0.882 [0.719, 1.00]
Ecc+Mod Reg+3PC	3	14.47	0.0023	0.615	0.882 [0.719, 1.00]
Ecc+ Reg+3PC	3	14.99	0.0018	0.631	0.882 [0.719, 1.00]
Ecc+3PC+Vol	3	16.87	0.0008	0.687	0.919 [0.799,1.00]
Ecc+ Reg+3PC+Vol	4	17.03	0.0019	0.691	0.919 [0.799,1.00]
Ecc+Mod Reg+3PC+Vol	4	17.02	0.0019	0.691	0.926 [0.804,1.00]

Analyzing all patients, Summary of Best Regression fits of combinations eccentricity, SCR, and Volume to Gleason score. AUC, Area Under Curve; R2, coefficient of determination; LL, Lower Limit Confidence Interval; UL Upper Limit 95% Confidence Interval; ECC, eccentricity(0.45 ACE Threshold); Mod_Reg, Modified Regularization; SCR, Reg, Regularized SCR; Vol, Volume (0.65 ACE threshold).