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PEDV challenge in piglets: experimental design.
| Group | Number of piglets | Recombinant adenovirus category | Dose | PEDV category | Dose | Route of administration |
|---|---|---|---|---|---|---|
| I | 3 | rAdV-ZW | 2 mL (1010TCID50) | PEDV | 1 mL (5×105TCID50) | Oral |
| II | 3 | rAdV-wild | 2 mL (1010TCID50) | PEDV | 1 mL (5×105TCID50) | Oral |
| III | 3 | PBS | 2 mL | PEDV | 1 mL (5×105TCID50) | Oral |
| IV | 3 | rAdV-ZW | 2 mL (1010TCID50) | PBS | 1 mL | Oral |
| V | 3 | PBS | 2 mL | PBS | 1 mL | Oral |
