Table 2.
Univariable Model | P-value | Multivariable Model | ||||||
---|---|---|---|---|---|---|---|---|
Mortality | ||||||||
no = 1173 | Yes = 738 | H.R | 95%CI | H.R | 95%CI | P-value | ||
Variables | ||||||||
Group, n (%) | ||||||||
Vertebroplasty | 38 (3.2) | 11 (1.5) | 1.09 | .60, 1.97 | .79 | .99 | .54, 1.80 | .97 |
Conservative | 155 (13.2) | 66 (9.0) | 1.66 | 1.28, 2.15 | <.0001 | 1.23 | .94, 1.61 | .12 |
Control | 980 (83.5) | 661 (89.5) | Ref | Ref | ||||
Gender | ||||||||
Male | 246 (51.0) | 927 (64.8) | 1.57 | 1.34, 1.83 | <.0001 | 1.53 | 1.31, 1.80 | <.0001 |
Female | 235 (49.0) | 503 (35.2) | Ref | Ref | ||||
Age, mean ±Std | 74.02 ± 5.64 | 78.46 ± 5.12 | 1.13 | 1.11, 1.15 | <.0001 | 1.12 | 1.10, 1.13 | <.0001 |
Chronic medication past 3 months, mean ±Stda | 10.89 ± 6.91 | 14.41 ± 8.27 | 1.06 | 1.05, 1.07 | <.0001 | 1.05 | 1.04, 1.06 | <.0001 |
Stratification | ||||||||
Male | N = 246 | N = 235 | ||||||
Group, n (%) | ||||||||
Vertebroplasty | 9 (3.7) | 3 (1.3) | 1.34 | .43, 4.22 | .62 | 1.12b | .35, 3.60 | .85 |
Conservative | 27 (11.0) | 24 (10.2) | 2.30 | 1.50, 3.56 | .0002 | 2.16b | 1.38, 3.38 | .001 |
Control | 210 (85.4) | 208 (88.5) | Ref | Ref | ||||
Female | N = 927 | N = 503 | ||||||
Group, n (%) | ||||||||
Vertebroplasty | 29 (3.1) | 8 (1.6) | 1.07 | .53, 2.15 | .85 | .92b | .54, 1.85 | .81 |
Conservative | 128 (13.8) | 42 (8.3) | 1.51 | 1.09, 2.08 | .013 | .99b | .71, 1.38 | .95 |
Control | 770 (83.1) | 453 (90.1) | Ref | Ref |
95% CI = 95% confidence interval.
aNumbers represent the mean prescriptions drawn from pharmacy 3 months prior to the fracture, analgesics excluded.
bAdjusted to age and Chronic medication past 3 months.