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. 2023 Feb 6;21:42. doi: 10.1186/s12916-023-02733-w

Table 3.

Odds ratios (95% confidence interval) for the increasing baPWV along with decreasing ABI across LDL-C vs. remnant cholesterol concordant/discordant groups and according to clinical cut-off points

Unadjusted odds ratio (95% CI) Adjusted odds ratio (95% CI)
RC percentile minus LDL-C percentile
 Concordant (within 10 percentiles), n = 749 Reference Reference
 Discordantly low RC, n = 1277 0.701 (0.586–0.837) 0.733 (0.604–0.889)
 Discordantly high RC, n = 1160 1.017 (0.85–1.217) 0.989 (0.816–1.199)
Cutpoints: LDL-C 130 mg/dL; RC 24 mg/dL
 LDL-C < 130 mg/dL and RC < 24 mg/dL, n = 1273 Reference Reference
 LDL-C ≥ 130 mg/dL and RC < 24 mg/dL, n = 393 1.229 (0.981–1.539) 1.276 (1.000–1.628)
 LDL-C < 130 mg/dL and RC ≥ 24 mg/dL, n = 986 1.378 (1.169–1.626) 1.445 (1.210–1.725)
 LDL-C ≥ 130 mg/dL and RC ≥ 24 mg/dL, n = 534 1.689 (1.385–2.06) 1.599 (1.289–1.983)
Cutpoints: LDL-C 100 mg/dL; RC 17 mg/dL
 LDL-C < 100 mg/dL and RC < 17 mg/dL, n = 301 Reference Reference
 LDL-C ≥ 100 mg/dL and RC < 17 mg/dL, n = 395 1.569 (1.154–2.132) 1.348 (0.966–1.879)
 LDL-C < 100 mg/dL and RC ≥ 17 mg/dL, n = 610 1.686 (1.281–2.218) 1.604 (1.190–2.161)
 LDL-C ≥ 100 mg/dL and RC ≥ 17 mg/dL, n = 1880 2.025 (1.601–2.561) 1.899 (1.464–2.463)

Odds ratio (OR) was estimated by ordinal logistics regression models adjusted for age, sex, body mass index, smoking status, systolic blood pressure, hypertension, diabetes, antihypertensive medication, lipid-lowering treatment

Abbreviations: CI Confidence interval, RC Remnant cholesterol, LDL-C Low-density lipoprotein cholesterol, HDL-C High-density lipoprotein cholesterol

(i) Concordant was defined as RC percentile and LDL-C percentile within ± 10 percentile units; (ii) discordantly low RC was defined as LDL-C percentile > RC percentile by 10 percentile units; and (iii) discordantly high RC was defined as RC percentile > LDL-C percentile by 10 percentile units