Figure 6.

Loss of chromosome 18 followed by loss of chromosome 4 is correlated with reduced survival in the MSKCC patient cohort

(A) Relation between Δ18 and Δ4 within the MSKCC patient cohort. Red and blue shading indicate enrichment and depletion compared to a random background distribution.

(B) Kaplan-Meier curve comparing survival between patient with Δ18 and Δ4 compared to patient withΔ18 and without Δ4.

(C) Absolute correlation between chromosomal alterations compared to the p value for the difference in hazard for the priming event alone compared to the priming event and the conditional event. Shading and size of the points indicate direction and magnitude of the difference in hazard.