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Quality control (QC) of rare-variant association tests
(A–C) The number of phenotypes (A), variants (B), and groups (i.e., gene-annotation pairs; C) before and after QC.
(D and E) After QC, the number of variants (D) and genes (E) are broken down by annotation and frequency bin (alternate allele frequency [AF] for variants, cumulative AF [CAF] for genes).
