Figure 2.
Top loci associated with asthma
(A) Index variants of 49 asthma-associated loci that are potentially novel. Missense variants and cis-eQTLs fine-mapped with PIP > 0.9 that overlapped with an index or tagging variant (r2 > 0.8) are annotated here. Frequency and meta-analysis effect size estimate of risk-increasing allele , with association p value, are shown on the right.
(B) Frequency and effect size of risk alleles of all 179 index variants. Previously reported genes with large effect sizes are highlighted.
See also Figures S1 and S3; Tables S2 and S4.