FIG. 9.

Comparison of hpa clusters involved in HPA catabolism in different proteobacteria from the γ subgroup. Arrows show the directions of gene transcription. Genes are indicated by blocks: red (regulatory genes), blue (transport genes), green (genes encoding the initial HPA monooxygenase), yellow (ring cleavage dioxygenase gene), and purple (genes encoding the meta-cleavage dehydrogenative route). A broken line indicates an unknown distance. The hpaR gene from K. pneumoniae corresponds to the previously characterized moaI gene (in parentheses). References of the sequences are as follows: E. coli (strain W) (accession no. Z37980), S. enterica serovar Dublin (accession no. AF144422), S. enterica serovar Typhimurium and Y. pestis (obtained from the ERGO database website) K. pneumoniae (accession no. L41068 and AJ000054 and ERGO database), and P. aeruginosa PAO1 (Pseudomonas Genome Project, at http://www.pseudomonas.com/).