Table 1.
Case count (and percentage) distributions by race and ethnicity and tumor characteristics for EOEC and LOEC, 1995-2018, United Statesa
| Patient and tumor characteristics | EOEC (age 0-49 years) | LOEC (age ≥50 years) | Total |
|---|---|---|---|
| (n = 116 750) | (n = 813 426) | (N = 930 176) | |
| Race and ethnicity | |||
| Hispanic | 17 734 (15.2) | 52 170 (6.4) | 69 904 (7.5) |
| Non-Hispanic Asian/Pacific Islander | 7112 (6.1) | 21 836 (2.7) | 28 948 (3.1) |
| Non-Hispanic Black | 9530 (8.2) | 76 071 (9.4) | 85 601 (9.2) |
| Non-Hispanic White | 79 844 (68.4) | 654 407 (80.5) | 734 251 (78.9) |
| Other/unknown | 2530 (2.2) | 8942 (1.1) | 11 472 (1.2) |
| Summary stage | |||
| Localized | 87 753 (75.2) | 564 014 (69.3) | 651 767 (70.1) |
| Regional | 17 927 (15.4) | 153 157 (18.8) | 171 084 (18.4) |
| Distant | 5565 (4.8) | 58 534 (7.2) | 64 099 (6.9) |
| Unknown | 5505 (4.7) | 37 721 (4.6) | 43 226 (4.6) |
| Grade | |||
| I (low) | 54 591 (46.8) | 265 568 (32.6) | 320 159 (34.4) |
| II | 26 287 (22.5) | 194 498 (23.9) | 220 785 (23.7) |
| III | 10 554 (9.0) | 142 385 (17.5) | 152 939 (16.4) |
| IV (high) | 2178 (1.9) | 33 926 (4.2) | 36 104 (3.9) |
| Unknown | 23 140 (19.8) | 177 049 (21.8) | 200 189 (21.5) |
| Histologic subtype | |||
| Endometrioid | 101 541 (87.0) | 642 678 (79.0) | 744 219 (80.0) |
| Non-endometrioid | 6683 (5.7) | 139 627 (17.2) | 146 310 (15.7) |
| Sarcoma | 5874 (5.0) | 11 818 (1.5) | 17 692 (1.9) |
| Other | 2621 (2.3) | 19 132 (2.4) | 21 753 (2.3) |
| Unknown | 31 (0.0) | 171 (0.0) | 202 (0.0) |
a
Mantel-Haenszel χ2 test was used to obtain the P values comparing EOEC with LOEC by race and ethnicity and tumor characteristics. All P values were less than .001. EOEC = early-onset endometrial cancer; LOEC = late-onset endometrial cancer.
b
Other/Unknown race and ethnicity includes Alaska Native, American Indian, other race, and unknown or missing race.