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Fluorescence microscopy of vaccinia virus-infected HeLa cells, labeled for actin (red) and vaccinia virus IMV particles (green), showing actin tail formation by vaccinia virus. (A) Actin tails on intracellular vaccinia virus. Bar, 50 μm. (B) Protrusions from the cell surface, formed by vaccinia virus, that contain actin tails and have viral particles at the tips. Bar, 10 μm. (Adapted from reference 32 with permission of the publisher.)
