. 2023 Jan 27;22(2):605–614. doi: 10.1021/acs.jproteome.2c00619

Table 1. Literature Review of Tools for Calculating PFS^a.

Year	Publication	Language	Availability	GUI	Site PFS^c	Visualization	PFS method^d
2022	H. Lin et al.⁶	Python	Public	Yes	Yes	Yes	Chem. and Therm.
2022	D. Childs et al.⁸^b	R	Public	N/A	No	Yes	Them.
2022	E. Walker et al.⁹	Mathematica (Wolfram).	In house	N/A	N/A	N/A	Chem.
2021	N. McCracken et al.¹⁰	R	Public	N/A	N/A	Yes	Therm.
2021	Y. Xu et al.¹¹	R	Public	N/A	N/A	N/A	Chem. and Therm.
2021	R. Ma et al.¹²	JAVA	In house	N/A	N/A	N/A	Chem.
2020	K. Lu et al.¹³	JAVA	In house	N/A	N/A	N/A	Chem.
2019	E. Walker et al.⁵	Mathematica (Wolfram).	In house	N/A	N/A	N/A	Chem.
2019	D. Childs et al.¹⁴	R	Public	N/A	No	Yes	Therm.
2018	H. Meng et al.¹⁵	Mathematica (Wolfram).	In house	N/A	N/A	N/A	Chem.

The table lists known tools for calculating PFS. Details were extracted from the method sections of 9 publications and one public repository for the programs used to fit the sigmoid curve and calculate PFS.

From public repository.

Lists if the program calculates the PFS of a given site of protein instead of peptide (discussed in depth in later sections).

Chem. stands for chemical denature method and Therm. stands for thermal denature method.

Table 1. Literature Review of Tools for Calculating PFSa.

Table 1. Literature Review of Tools for Calculating PFS^a.