Figure 2.

FLL suppresses bone loss and reduces fat weight in OVX mice. (A) Body weights of OVX mice eight weeks post-operatively. Treatment with FLL decreased body weight significantly. (B) Bone mineral density (BMD) in the femurs of OVX mice decreased significantly compared to the sham group, and estrogen and FLL significantly augmented BMD in OVX mice. (C,D) The body fat and lean content of each group were evaluated by an NMR body composition analyzer after eight weeks. (E–G) The indices for liver, kidney, and spleen among groups. ^#p < 0.05 compared with sham; ^##p < 0.01 compared with sham; *p < 0.05 compared OVX; **p < 0.01 compared OVX (n = 10).