Differentially expressed genes in the inner medulla of male and female saline-injected mice. (A) A volcano plot of the significant (adjusted p value <0.05) differentially expressed genes in males (blue) compared to females (pink). (B–G) Comparisons of the inner medullary endothelin (Edn) related transcripts from female and male saline-injected mice from this study. Normalized counts from the analyses package DESeq2 are reported and p values are adjusted p values from the Wald test with Benjamini and Hochberg correction reported. (B) Edn1, (C) Edn3, (D) Ece1, (E) Ece2, (F) Ednra, and (G) Ednrb. Sample size: females = 7 and males = 6.