Skip to main content
. Author manuscript; available in PMC: 2023 Feb 7.
Published in final edited form as: Can J Physiol Pharmacol. 2022 Jun 15;100(9):868–879. doi: 10.1139/cjpp-2022-0126

Table 2.

Characteristics of the mice used in the study.

Female Male Two-factor ANOVA
Saline Cisplatin Saline Cisplatin P sex P cisplatin P Interaction
Sample size 7 5 6 6
Age 9 9 9 9
Starting mass g 20.38 (0.32) 20.77 (0.55) 26.49 (0.69) * 27.70 (0.41) * <0.001 0.13 0.43
Change in mass % −0.55 (1.49) 13.2 (3.80)* 0.56 (0.92) 14.33 (2.78)* 0.99 <0.001 0.62
Total kidney mass mg 0.24 (0.004) 0.21 (0.004) 0.30 (0.01) 0.29 (0.006) <0.001 0.072 0.38
Kidney/starting body mass mg/g 11.56 (0.13) 10.20 (0.21) * 11.23 (0.36) 10.43 (0.26) 0.85 0.0006 0.30
Kidney/dissection body mass mg/g 11.64 (0.12) 12.03 (0.57) 11.13 (0.33) 12.12 (0.55) 0.68 0.069 0.37
Heart mass mg/dL 0.11 (0.008) 0.092 (0.001) 0.13 (0.007) 0.12 (0.006) 0.0045 0.073 0.76
Heart/starting body mass mg/g 5.10 (0.32) 4.48 (0.14) 4.79 (0.19) 4.20 (0.19) 0.20 0.016 0.95
Heart/dissection body mass mg/g 5.20 (0.34) 5.26 (0.14) 4.78 (0.16) 4.96 (0.17) 0.12 0.60 0.77
Plasma creatinine mg/dL 0.14 (0.01) 0.16 (0.03) 0.13 (0.007) 0.25 (0.06) * 0.19 0.019 0.11
Plasma urea mg/dL 53.2 (6.6) 76.7 (15.6) 66.9 (4.2) 110.7 (20.5) 0.072 0.014 0.43

Note: Mean (standard error of mean) values are reported. Bold represents statistical significance.

*

indicates significant difference from post hoc Tukey’s analysis.