Table 1:
Baseline characteristics of the study population and high-risk subgroup.
| Total Population | High-Risk Subgroup | |||
|---|---|---|---|---|
| Including Validated Heart Failure c n = 2041 | Excluding Validated Heart Failure c n = 1996 | Including Validated Heart Failure c n = 1391 | Excluding Validated Heart Failure c n = 1348 | |
|
| ||||
| Women gender, n (%) Age, years, mean (SD) Age ≥ 65 years, n (%) BMI, mean (SD) |
1058 (52%) 63 (11) 817 (40%) 28 (5) |
1040 (52%) 62.5 (10) 784 (39%) 28 (5) |
633 (46%) 63.5 (10) 601 (43%) 29 (5) |
617 (46%) 63 (10) 569 (42%) 29 (5) |
|
| ||||
| Estimated GFRb, mean (SD) NT-proBNP, median (Q1,Q3) |
84 (23) 68 (28, 146) |
85 (23) 66 (28, 140) |
83 (24) 72 (28, 167) |
84 (24) 69 (27, 158) |
|
| ||||
| Diabetes, n (%) Hypertension, n (%) Coronary artery disease, n (%) Smoking (current or previous), n (%) Clinical heart failurec, n (%) |
151 (7%) 575 (28%) 249 (12%) 1020 (50%) 45 (2.2%) |
138 (7%) 546 (27%) 215 (11%) 994 (50%) 0 (0%) |
151 (11%) 575 (41%) 249 (18%) 1020 (74%) 43 (3.1%) |
138 (10%) 546 (41%) 215 (16%) 994 (74%) 0 (0%) |
|
| ||||
| Ejection fraction ≤ 50%, n (%) Ejection fraction ≤ 40%, n (%) Ejection fraction ≤ 35%, n (%) |
123 (6%) 40 (2%) 20 (1%) |
98 (5%) 22 (1%) 9 (1%) |
109 (8%) 37 (3%) 19 (1%) |
86 (6%) 20 (2%) 8 (1%) |
High-risk subgroup was defined as the presence of one or more of the following: diabetes, hypertension, coronary artery disease, or current/previous smoking history.
a
Abbreviations: BMI = body mass index, GFR = glomerular filtration rate, NT-proBNP = N-terminal pro-B-type natriuretic peptide, SD = standard deviation
b
Glomerular filtration rate calculated using the Modification of Diet in Renal Disease (MDRD) equation.
c
Clinical heart failure regardless of the ejection fraction confirmed by trained nurse abstractors using Framingham criteria.