Table 5. Comparisons of adverse events between the ATB (-) and ATB (+) groups.
| Adverse events | ATB (-) | ATB (+) | p value |
|---|---|---|---|
| n = 86 | n = 19 | ||
| Proteinuria, n (%) | 38 (44.2) | 7 (36.8) | 0.558 |
| Hypertension, n (%) | 36 (41.9) | 7 (36.8) | 0.687 |
| Fatigue, n (%) | 30 (34.9) | 3 (15.8) | 0.105 |
| Decreased appetite, n (%) | 22 (25.6) | 2 (10.5) | 0.230 |
| Fever, n (%) | 13 (15.1) | 3 (15.8) | 1.000 |
| Rash, n (%) | 13 (15.1) | 2 (10.5) | 1.000 |
| Increased AST or ALT, n (%) | 12 (14.0) | 3 (15.8) | 0.733 |
| Diarrhea, n (%) | 8 (9.3) | 4 (21.1) | 0.223 |
| Any infection, n (%) | 7 (8.1) | 1 (5.3) | 1.000 |
| Any adverse event of grade ≥ 3, n (%) | 25 (29.1) | 7 (36.8) | 0.505 |
| Any irAE treated with steroids, n (%) | 5 (5.8) | 1 (5.3) | 1.000 |
Abbreviations: AE, adverse event; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ATB, antibiotics; irAE, immune-related adverse event.