TABLE 1.
Main characteristics of included studies.
| Author | Year | Country | Constipation criterion | BP quality assessment | BP regimen | NP (f) | Age (M± SD) |
|---|---|---|---|---|---|---|---|
| Arezzo, A | 2000 | Germany | Asked if he or she experienced constipation | Non-validate score | Senna + MgSO4 | 40 (NA) | NA |
| 4L PEG | 43 (NA) | NA | |||||
| NaP | 48 (NA) | NA | |||||
| De Salvo, L | 2006 | Italy | Rome II | Non-validate score | Senna + MgSO4 | 36 (NA) | 61.4 ± 12.0 |
| 2L PEG + bisacodyl | 40 (NA) | 60.5 ± 10.9 | |||||
| NaP | 25 (NA) | 61.9 ± 12.6 | |||||
| Lee, H | 2010 | Korea | Rome III | BP quality grading | Probiotic 14 days + NaP | 51 5) | 40.5 ± 11.4 |
| NaP | 53 5) | 42.2 ± 11.7 | |||||
| Tajika, M | 2012 | Japan | <2 bowel movements per week more than a year | Aronchick’s criteria | Mosapride+2L PEG | 16 (11) | 67.3 ± 8.6 |
| 2L PEG | 5 4) | 67.8 ± 10.1 | |||||
| Tian, Xia | 2012 | China | Asked if he or she experienced constipation | BP quality grading | Probiotic 3 days + mosapride 3 days +2L PEG | 86 (40) | NA |
| Mosapride 3 days +2L PEG | 82 (44) | NA | |||||
| 2L PEG | 80 (42) | NA | |||||
| Pereyra, Lisandro | 2013 | Argentina | Rome II | BP quality grading | NaP | 22 (NA) | 59 ± 13.2 |
| NaP + bisacodyl | 20 (NA) | 57 ± 11.1 | |||||
| 4L PEG | 15 (NA) | 60 ± 13.8 | |||||
| 2L PEG + bisacodyl | 20 (NA) | 59 ± 10.9 | |||||
| Parente, Fabrizio | 2015 | Italy | Rome III | OBPS | 2L PEG + simethicone + citrates + bisacodyl | 193 (105) | 60 ± 13 |
| 4L PEG | 189 (113) | 59 ± 14 | |||||
| Li, Y | 2017 | China | 1 or 2 on the Bristol Stool Form Scale | BBPS | 2L PEG + bisacodyl | 234 (160) | 52.1 ± 9.8 |
| 2L PEG | 233 (156) | 52.2 ± 9.7 | |||||
| Yu, Z. B | 2018 | China | Rome III | BBPS | Lactulose 2 days+2L PEG | 36 (NA) | NA |
| 2L PEG + senna | 36 (NA) | NA | |||||
| 2L PEG | 36 (NA) | NA | |||||
| Zhong, Shishun | 2018 | China | Chinese chronic constipation guide | BBPS | Testa triticum tricum 7 days +3L PEG | 93 (61) | 52.9 ± 12.3 |
| 3L PEG | 97 (60) | 53.3 ± 12.6 | |||||
| Chancharoen, A | 2019 | Thailand | Rome III or a score of 1 or 2 on the Bristol Stool Form Scale | OBPS | 4L PEG + pre-2L PEG | 37 (23) | 57.6 ± 9.4 |
| 4L PEG | 39 (25) | 59.2 ± 7.2 |
BP, bowel preparation; BBPS, Boston Bowel Preparation Scale; OBPS, Ottawa Bowel Preparation Scale; NaP, sodium phosphate; PEG, polyethylene glycol; NA, not available; NP, number of patients; f, female; M±SD, mean ± standard deviation.