Table 3.

Independent risk factors for postfingolimod disease activity.

	Coefficient	SD	OR	CI	p value	N
(Intercept)	2.788	1.190	16.251	[1.730, 193.338]	NA	94
Age at diagnosis (effect of 1 year less)	0.094	0.033	1.098	[1.033, 1.179]	<0.01	VIF = 1.12
Disease durationa (effect of 1 year less)	0.154	0.046	1.167	[1.074, 1.287]	<0.01	VIF = 1.17
MRI activity under FGL present (versus absent)	1.070	0.550	2.916	[1.018, 8.982]	0.0462	VIF = 1.09

CI, confidence interval; FGL, fingolimod; NA, not available; OR, odds ratio; SD, standard deviation; VIF, variance inflation factor.

Multivariate logistic model with 94 complete cases that shows that younger age at diagnosis, shorter disease duration, and presence of MRI activity under FGL are independent risk factors for postfingolimod disease activity.

^aNote that disease duration was calculated at fingolimod discontinuation.