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. 2022 Nov 9;31(2):195–201. doi: 10.1038/s41431-022-01220-9

Table 1.

Auxological Data at baseline and after 1 and 2 years of rGH therapy.

CAa, years BAb, years HTc, cm (SDS) GVd, cm/year (SDS) ΔHTa-HTabaseline, cm (SDS) ΔTHe-HTa (SDS) rGHf dose (mcg/kg/day)
Twin A (GHDg)
  Baseline 6.6 6.3 105 (−2.75) 3.8 (−2.5) 3.42 0.025
  1 year 7.6 6.7 112.3 (−2.23) 7.5 (2.1) 7.3 (0.52) 2.90 0.022
  2 years 8.7 7.2 119.6 (−1.95) 6.2 (0.9) 14.6 (0.82) 2.62 0.022
Twin B (SGAh)
  Baseline 6.6 6.7 104 (−2.95) 4.3 (−2.0) 3.62 0.035
  1 year 7.6 7.9 113.8 (−2.07) 9.5 (4.1) 9.4 (0.88) 2.74 0.032
  2 years 8.7 8.7 122.1 (−1.53) 7.9 (2.9) 18.1 (1.42) 2.20 0.033

aChronological Age.

bBone Age.

cHeight.

dGrowth Velocity.

eTarget Height.

fRecombinant Growth Hormone.

gGrowth Hormone Deficiency.

hSmall for Gestational Age.