Table 2.

Hormonal and biochemical at baseline and after 1 and 2 years of rGH therapy.

	IGF-Ia, ng/mL (nv 65–225)	IGF-Ia, SDS	Glycemia, mg/dL (nv 80–100)	Insulin, IU/L (nv 1.8–24)	TSHb, mIU/L (nv 0.26–4.2)	Free T4c, pg/mL (nv 8–17)
Twin A (GHDd)
Baseline	53	−2.02	83	8.0	1.76	10.6
1 year	172	0.66	90	10.4	–	–
2 years	164	0.49	91	11.2	1.5	10.3
Twin B (SGAe)
Baseline	52	−2.05	84	7.3	1.83	12.7
1 year	149	0.1	89	11.8	–	–
2 years	170	0.61	92	8.4	1.37	11.8

¹Insulin-like Growth Factor-I.

^bThyroid Stimulating Hormone.

^cThyroxine.

^dGrowth Hormone Deficiency.

^eSmall for Gestational Age.