TABLE 3.
Hydrolytic clearance parameters of EA and EB incubated with RLMs (mean ± SD; n = 3).
| Compound | t 1/2 (min) | CL int [ml/(min·kg)] | CL h [ml/(min·kg)] | Metabolism rate (%) |
|---|---|---|---|---|
| EA | 16.19 ± 0.51 | 153.51 ± 4.94 | 40.60 ± 0.34 | 94.61 ± 0.4 |
| EB | 20.89 ± 0.81 | 118.99 ± 4.69 | 37.70 ± 0.46 | 89.90 ± 0.9 |