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. 2022 Jun 29;79(1):193–204. doi: 10.1007/s13105-022-00899-0

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Fig. 5 — Exosomal miRNAs promote activation of quiescent hepatic stellate cells (qHSCs). Exosomes derived from the primary PDAC tumour cells (A) or PDAC circulating tumour cells (B) deliver to the liver miRNAs that activate qHSCs and potentially mediate the formation of a hepatic pre-metastatic niche