TABLE 5.

Percentage changes in cholesterol content by GP-HPLC analysis from baseline to week 16.

		PEMA (n = 58)	OMEGA-3 (n = 61)	P
Subclass	Particle diameter (nm)	Median (Min-Max)	Median (Min-Max)
CM	>90	−69.8(−96.3 to 33.2)	−55.7(−93.8 to 48.1)	0.009
	75	−58.7(−93.8 to 62.8)	−45.9(−89.9 to 41.4)	0.019
L-VLDL	64	−49.0(−87.1 to 90.5)	−38.4(−82.8 to 45.4)	0.016
	53.6	−49.0(−86.9 to 76.8)	−28.6(−74.7 to 59.4)	<0.001
	44.5	−17.2(−69.7 to 111.1)	−12.7(−64.0 to 41.7)	0.450
M-VLDL	36.8	−30.9(−79.1 to 76.3)	−11.3(−55.1 to 59.7)	0.001
S-VLDL	31.3	31.5(−47.8 to 445.0)	−12.5(−55.0 to 108.6)	<0.001
L-LDL	28.6	30.9(−30.0 to 449.1)	−5.9(−35.9 to 137.9)	<0.001
M-LDL	25.5	14.7(−42.7 to 111.9)	−1.6(−44.1 to 86.5)	0.002
S-LDL	23.0	4.5(−61.9 to 109.7)	0.2(−45.5 to 162.5)	0.669
VS-LDL	20.7	7.3(−64.9 to 123.7)	3.9(−46.1 to 162.5)	0.770
	18.6	−3.4(−54.2 to 79.0)	12.0(−52.2 to 125.8)	0.022
	16.7	−1.7(−54.9 to 66.9)	8.1(−29.1 to 102.4)	0.001
VL-HDL	15.0	−4.2(−69.4 to 71.8)	8.9(−56.6 to 120.0)	0.003
	13.5	−41.9(−83.0 to 67.5)	17.5(−55.7 to 221.5)	<0.001
L-HDL	12.1	−6.3(−67.6 to 106.3)	23.4(−43.7 to 163.4)	<0.001
M-HDL	10.9	45.0(−17.5 to 120.6)	7.7(−30.6 to 73.8)	<0.001
S-HDL	9.8	45.2(−15.6 to 137.2)	−3.0(−37.4 to 52.1)	<0.001
VS-HDL	8.8	47.4(−9.5 to 132.6)	−0.7(−30.1 to 56.4)	<0.001
	7.6	22.5(−12.7 to 97.8)	2.8(−15.7 to 44.2)	<0.001

The data are presented as medians (Min-Max). P values are for comparison between the two groups. Lipoprotein subclasses are listed in descending order of particle diameter from CM to VS-HDL. CM, chylomicron; L-VLDL, large very low-density lipoprotein; M-VLDL, medium very low-density lipoprotein; S-VLDL, small very low-density lipoprotein; L-LDL, large low-density lipoprotein; M-LDL, medium low-density lipoprotein; S-LDL, small low-density lipoprotein; VS-LDL, very small low-density lipoprotein; VL-HDL, very large high-density lipoprotein; L-HDL, large high-density lipoprotein; M-HDL, medium high-density lipoprotein; S-HDL, small high-density lipoprotein; VS-HDL, very small high-density lipoprotein.