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. Author manuscript; available in PMC: 2023 Feb 8.
Published in final edited form as: J Alzheimers Dis. 2023;91(3):977–987. doi: 10.3233/JAD-220680

Fig. 1.

Fig. 1.

Study flowchart. 1SNP, single nucleotide polymorphisms; 2MAF, minor allele frequency; 3ADNI, Alzheimer’s Disease Neuroimaging Initiative; 4NACC, National Alzheimer’s Coordinating Center; 5BFDP, Bayesian False Discovery Probability; 6LD, linkage disequilibrium; 7PRS, polygenic risk score; 8CSF, cerebrospinal fluid; 9eQTL, expression quantitative trait loci; 10GTEx, genotype-tissue expression; 11Other covariates included age at baseline, gender, race, years of education, top three principal components from the genetic data and the number of allele copies of APOE E2 and APOE E4.