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. Author manuscript; available in PMC: 2023 Feb 8.
Published in final edited form as: J Alzheimers Dis. 2023;91(3):977–987. doi: 10.3233/JAD-220680

Table 2.

Performance of models without/with AD PRS constructed with the identified 6 SNPs

Model PRS
AUC p
ADNI dataset
 Non-PRS model1 0.682
 PRS model2 0.720 0.0033
NACC dataset
 Non-PRS model1 0.586
 PRS model2 0.609 0.0123
1

The model including age, sex, education, race, the top 3 PCs, the copy numbers of APOE E2, and E4.

2

The model including age, sex, education, race, the top 3 PCs, the copy numbers of APOE E2, APOE E4 and PRS.

3

Results of PRS model versus non-PRS model by using the function of timeROC package, as the extension of DeLong test.