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Association results of PRS and different markers in NACC dataset
| Phenotype | NACC-PRS | ||||
|---|---|---|---|---|---|
| #Subjects | #Observations | beta1 | se1 | p 1 | |
| Cognitive assessments | |||||
| CDR-SB | 1373 | 5,270 | 0.048 | 0.033 | 0.155 |
| MMSE | 1239 | 4,329 | −0.031 | 0.063 | 0.627 |
Adjusted for age at baseline, sex, years of education, race, top three PCs, and the allele copies of APOE E4 and APOE E2.
