Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jul 12;39(2):177–193. doi: 10.1007/s12264-022-00910-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 3 — Generation and characterization of the TNT mouse model. A Schematic of the generation of the TNT mouse model. B IHC showing the expression of the neuronal injury marker ATF3 and NPY in NPY-Cre; Ai3 mice after TNT surgery (scale bars, 200 μm). C–F Behavioral tests of the TNT mouse model including phantom pain (C), n = 5–8, stump pain (D), n = 5–8, cold allodynia (E), n = 5–8, and heat hyperalgesia (F), n = 5. (*P <0.05, **P <0.01, ***P <0.001, two-way ANOVA). G qRT-PCR results for the expression of Tmem63a in the DRGs from TNT mouse models (n = 10–11; *P <0.05, **P <0.01, two-way ANOVA). H qRT-PCR results for the expression of Tmem63a in DRGs from chemotherapy (PTX) mouse models (n = 4; *P <0.05, one-way ANOVA).