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. 2023 Jan 25;13:1073971. doi: 10.3389/fimmu.2022.1073971

Table 1.

Expression of HIF-1ɑ in inflammatory autoimmune diseases.

Diseases Sample Expression References
SLE Urine Increasea 116
Glomerulus and Tubular Increasea,b 9
CD4+T cell Increasea 2
RA Synovial tissue Increasea 10, 120, 121
Serum Increaseb 123126
IBD Intestinal cells Increasea 140
SSc Skin tissue Increasea 162
Psoriasis Skin lesion Increasea 12, 164166
Serum Increasea 167
MS White matter Increasea 170
Tissue Increaseb 171
T1DM Islet tissue Increasea 175

SLE, systemic lupus erythematosus; RA, rheumatoid arthritis; IBD, inflammatory bowel disease; SSc, systemic sclerosis; MS, multiple sclerosis; T1DM, type 1 diabetes mellitus.

a

Human.

b

Mice.