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. 2023 Feb 7;14(2):90. doi: 10.1038/s41419-022-05547-5

Fig. 6. PDHB-AS interacts with RBMX to affect cisplatin resistance in CC cells.

Fig. 6

A IC50 values to cisplatin in HeLa and SiHa cells transfected with indicated plasmids including pcDNA3.1, pcDNA3.1-PDHB-AS, pcDNA3.1-PDHB-AS + si-NC, or pcDNA3.1-PDHB-AS + si-RBMX were detected. B IF and FISH experiments detected the distribution of PDHB-AS and RBMX in HeLa and SiHa cells with PDHB-AS overexpression. C DNA damage in HeLa and SiHa cells transfected with pcDNA3.1-PDHB-AS upon cisplatin treatment was detected by comet assays. **P < 0.01.