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. 2023 Jan 25;10:1115389. doi: 10.3389/fcvm.2023.1115389

Figure 3.

Figure 3

Left ventricular mass index. Left ventricular mass index (LVMI) was calculated from body surface area, and left ventricular mass was estimated using the Devereux equation. In (A), we compare LVMI of patients with severe acute COVID-19 (red) or pediatric inflammatory multiorgan syndrome (PIMS, blue) at the time of disease onset and last follow-up (f/u) visit 3–6 months later. At both time points, there was no significant difference in LVMI between the two diagnoses (p = 0.971 at disease onset; p = 0.850 at f/u). However, both groups saw a significant reduction in LV mass (not shown) and LVMI at f/u. As shown in (B), there was also no significant difference in LVMI between patients with PIMS with or without (green) late gadolinium enhancement (LGE) in cardiac MRI at the time of disease onset (p = 0.660) or f/u (p = 1). The difference n LVMI between non-LGE PIMS was more pronounced (p = 0.023) than in PIMS with LGE (p = 0.0625). See also Supplementary Figure 3 for LV z scores and connected dot plots.