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. 2023 Jan 25;13:978985. doi: 10.3389/fonc.2023.978985

Table 3.

Cumulative frequency of distant metastasis sites according to molecular subtypes.

Total (%) Luminal A (%) Luminal B (%) HER2-enriched (%) Triple negative (%) P value
Number of distant metastasis (%)
1 1249 (53.0%) 187 (55.0%) 528 (53.1%) 261 (50.2%) 273 (54.3%) 0.472
≥2 1109 (47.0%) 153 (45.0%) 467 (46.9%) 259 (49.8%) 230 (45.7%)
Bone 935 (39.1%) 178 (51.1%) 452 (44.7%) 150 (28.7%) 155 (30.5%) <0.001
Liver 569 (23.8%) 69 (19.8%) 265 (26.2%) 148 (29.1%) 87 (16.6%) <0.001
Lung 729 (30.5%) 85 (24.4%) 299 (29.5%) 189 (36.1%) 156 (30.6%) 0.002
Brain 81 (3.4%) 6 (1.7%) 32 (3.2%) 20 (3.8%) 23 (4.5%) 0.145
visceral metastases* 1845 (77.1%) 275 (79.0%) 811 (80.1%) 369 (70.6%) 390 (76.6%) <0.001

* including liver, lung, brain, adrenal gland and ovary, etc.