Fig. 2. Expression of miR-1246/DYRK1A/NFATc1 in scalp tissues. (A) mRNA levels of miR-1246, DYRK1A, and NFATc1 in severe active AA and HC. (B) Protein expression of NFATc1 in severe active AA and HC. (C) Immunohistochemistry of NFATc1 in scalp tissues (×400). (D) Number of NFATc1 positive cells under high power field (mean±standard deviation). AA: alopecia areata, HC: healthy controls, miR-1246: microRNA-1246, DYRK1A: dual-specific tyrosine phosphorylation-regulated kinase 1A, NFAT: nuclear factor of activated T cells. ^*p<0.05, ^**p<0.01.