Table 2.

Factors associated with receipt of full vaccination and booster doses based on multivariable Cox proportional hazards models with interaction terms for time since diagnosis with cancer type and receipt of recent systemic therapy^a

Variables	Full vaccination (n = 356 535)	Booster doses (n = 306 212)
	HR (95% CI)	HR (95% CI)
Age
Point estimate at 40 y	1.06 (1.05 to 1.06)	1.09 (1.08 to 1.09)
Point estimate at 80 y	1.00 (0.99 to 1.00)	0.95 (0.94 to 0.95)
Sex
Female	1.08 (1.08 to 1.09)	1.01 (1.00 to 1.01)
Male	Referent	Referent
Cancer type
Hematologic vs solid cancer (diagnosed in the last year)	1.20 (1.16 to 1.24)	1.37 (1.32 to 1.43)
Hematologic vs solid cancer (diagnosed 1-5 y prior)	1.09 (1.07 to 1.11)	1.22 (1.20 to 1.24)
Hematologic vs solid cancer (diagnosed 5-10 y prior)	1.03 (1.01 to 1.05)	1.12 (1.10 to 1.14)
Recent systemic therapy
Recent systemic therapy vs none (diagnosed in last year)	1.02 (1.00 to 1.04)	1.01 (0.98 to 1.03)
Recent systemic therapy vs none (diagnosed 1-5 y prior)	1.00 (0.99 to 1.01)	1.07 (1.06 to 1.08)
Recent systemic therapy vs none (diagnosed 5-10 y prior)	1.12 (1.12 to 1.14)	1.11 (1.09 to 1.13)
Immigration status
Recent	0.74 (0.72 to 0.76)	0.67 (0.65 to 0.70)
Nonrecent	0.80 (0.79 to 0.81)	0.71 (0.70 to 0.73)
Long-term resident/Canadian	Referent	Referent
Socioeconomic status
Rural	0.87 (0.86 to 0.89)	0.88 (0.86 to 0.90)
Q1-low	0.82 (0.81 to 0.84)	0.86 (0.84 to 0.88)
Q2	0.87 (0.85 to 0.88)	0.89 (0.88 to 0.91)
Q3	0.90 (0.89 to 0.91)	0.91 (0.89 to 0.92)
Q4	0.94 (0.93 to 0.95)	0.93 (0.92 to 0.94)
Q5-high	Referent	Referent
Aggregated clinical groups
0-4 ADGs	Referent	Referent
5-9 ADGs	1.36 (1.35 to 1.38)	1.06 (1.05 to 1.07)
10+ ADGs	1.30 (1.29 to 1.32)	1.04 (1.03 to 1.05)
Residential Instability quintile
Q1- low	Referent	Referent
Q2	0.99 (0.98 to 1.00)	1.02 (1.00 to 1.03)
Q3	1.00 (0.99 to 1.01)	1.04 (1.03 to 1.06)
Q4	1.04 (1.02 to 1.05)	1.09 (1.07 to 1.11)
Q5- high	1.02 (1.00 to 1.03)	1.12 (1.10 to 1.14)
Material Deprivation quintile
Q1-low	Referent	Referent
Q2	0.95 (0.94 to 0.96)	0.96 (0.95 to 0.97)
Q3	0.91 (0.90 to 0.92)	0.93 (0.92 to 0.95)
Q4	0.86 (0.85 to 0.88)	0.89 (0.87 to 0.90)
Q5-high	0.80 (0.78 to 0.81)	0.81 (0.80 to 0.83)
Dependency quintile
Q1- low	Referent	Referent
Q2	1.04 (1.02 to 1.05)	1.02 (1.01 to 1.04)
Q3	1.05 (1.04 to 1.07)	1.04 (1.02 to 1.05)
Q4	1.07 (1.06 to 1.08)	1.05 (1.04 to 1.07)
Q5- high	1.13 (1.12 to 1.15)	1.07 (1.06 to 1.09)
Ethnic Concentration quintile
Q1-low	Referent	Referent
Q2	1.00 (1.00 to 1.02)	1.02 (1.01 to 1.04)
Q3	1.01 (1.00 to 1.02)	1.03 (1.01 to 1.04)
Q4	1.03 (1.01 to 1.04)	1.01 (1.00 to 1.03)
Q5- high	1.00 (0.99 to 1.02)	0.97 (0.95 to 0.99)
Resident of a long-term care facility
Yes	—	1.05 (1.02 to 1.09)
No	—	Referent
COVID-19 infection before first dose
Yes	1.12 (1.10 to 1.15)	0.87 (0.84 to 0.90)
No	Referent	Referent
Regional Public Health Authority
Central East	0.83 (0.81 to 0.84)	1.15 (1.13 to 1.18)
Central West	0.86 (0.85 to 0.87)	1.05 (1.04 to 1.07)
Durham	0.95 (0.93 to 0.97)	0.98 (0.95 to 1.00)
Eastern	0.83 (0.81 to 0.84)	1.22 (1.20 to 1.25)
North	0.90 (0.88 to 0.91)	1.08 (1.05 to 1.10)
Ottawa	0.93 (0.91 to 0.94)	1.28 (1.24 to 1.30)
Peel	0.93 (0.91 to 0.94)	0.85 (0.84 to 0.87)
South West	0.87 (0.86 to 0.88)	1.15 (1.13 to 1.17)
York	0.98 (0.97 to 1.00)	0.96 (0.94 to 0.98)
Toronto	Referent	Referent
Time to second dose
Increment: week	—	1.07 (1.07 to 1.07)
Omicron
After Omicron	—	1.05 (1.03 to 1.06)
Before Omicron	—	Referent

^aHR = hazard ratio; CI = confidence interval; ADG = aggregated diagnosis groups.