Table 4.
Harrell’s concordance index (95% confidence interval) for 3 prostate cancer clinical endpoints using race and ethnicity and family history, with or without PHS290a
| Clinical endpoints | Race and ethnicity and family history | Race and ethnicity and family history and PHS290 |
|---|---|---|
| Fatal prostate cancer | 0.597 (0.579 to 0.618) | 0.701 (0.684 to 0.721) |
| Metastatic prostate cancer | 0.595 (0.587 to 0.606) | 0.693 (0.684 to 0.703) |
| Prostate cancer | 0.583 (0.581 to 0.586) | 0.688 (0.685 to 0.690) |
a
This multivariable analysis was limited to the 378 366 participants who provided family history information in baseline survey data. Concordance index was greater with addition of PHS290 for each endpoint (P < .001).